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Subnetworks conserved in human and mouse

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Mouse Subnetwork Human Subnetwork
G 7553 ISLR 99 TNXB 402 COL3A1 99--402 15190 PGF 99--15190 1509 NRP1 14854 THY1 1509--14854 2411 SEMA3C 1509--2411 2188 LOC100044161 1509--2188 1509--402 1509--15190 1146 PDGFRA 1509--1146 14854--2411 14854--2188 14854--402 14854--1146 2411--2188 2411--402 2411--15190 2411--1146 2188--402 2188--15190 2188--1146 402--1146 15190--1146 G 7553 ISLR 99 TNXB 7553--99 14854 THY1 7553--14854 402 COL3A1 7553--402 1146 PDGFRA 7553--1146 99--14854 2188 SEMA3A 99--2188 99--1146 1509 NRP1 1509--2188 1509--402 15190 PGF 1509--15190 1509--1146 14854--2188 14854--402 14854--15190 14854--1146 2411 SEMA3C 2411--2188 2188--1146 402--1146
Cytoscape file Cytoscape file

Confidence Information

Average fold change (normalized) 0.217394
Number of real subnetworks at this score 42
Number of random subnetworks at this score 0.80 +/- 0.96

Mouse genes' details

Gene Name Actual fold change Normalized fold change
ISLR 0.78 -0.50
TNXB 0.58 -0.37
NRP1 0.38 -0.39
THY1 1.63 0
SEMA3C 0.55 -0.37
LOC100044161 0.67 0
COL3A1 0.41 -0.28
PGF 0.80 -0.11
PDGFRA 0.56 -0.32

Human genes' details

Gene Name Absolute fold change Normalized fold change
ISLRmmunoglobulin superfamily containing leucine-rich repeat 0.31 -0.50
TNXBtenascin XB 0.43 -0.37
NRP1neuropilin 1 0.41 -0.39
THY1hy-1 cell surface antigen 0 0
SEMA3Cma domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.42 -0.37
SEMA3Ama domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0 0
COL3A1collagen, type III, alpha 1 0.53 -0.28
PGFplacental growth factor 0.78 -0.11
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide 0.48 -0.32

Go Enrichment

Mouse GO Terms Human GO Terms
GO:0001568 blood vessel development 4.57e-06 5 7 233 14467 COL3A1,SEMA3C,PGF,THY1,NRP1
GO:0001944 vasculature development 4.87e-06 5 7 236 14467 COL3A1,SEMA3C,PGF,THY1,NRP1
GO:0048514 blood vessel morphogenesis 2.48e-04 4 7 198 14467 SEMA3C,PGF,THY1,NRP1
GO:0009887 organ morphogenesis 5.98e-04 5 7 620 14467 SEMA3C,PGF,THY1,NRP1,PDGFRA
GO:0030198 extracellular matrix organization and biogenesis 1.96e-03 3 7 94 14467 COL3A1,TNXB,PDGFRA
GO:0048513 organ development 2.25e-03 6 7 1575 14467 COL3A1,SEMA3C,PGF,THY1,NRP1,PDGFRA
GO:0001525 angiogenesis 6.63e-03 3 7 141 14467 PGF,THY1,NRP1
GO:0048731 system development 6.68e-03 6 7 1894 14467 COL3A1,SEMA3C,PGF,THY1,NRP1,PDGFRA
GO:0043062 extracellular structure organization and biogenesis 6.77e-03 3 7 142 14467 COL3A1,TNXB,PDGFRA
GO:0030199 collagen fibril organization 9.02e-03 2 7 21 14467 COL3A1,TNXB
GO:0048856 anatomical structure development 1.30e-02 6 7 2121 14467 COL3A1,SEMA3C,PGF,THY1,NRP1,PDGFRA
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.59e-02 3 7 189 14467 SEMA3C,NRP1,PDGFRA
GO:0009653 anatomical structure morphogenesis 1.75e-02 5 7 1234 14467 SEMA3C,PGF,THY1,NRP1,PDGFRA
GO:0007275 multicellular organismal development 2.72e-02 6 7 2406 14467 COL3A1,SEMA3C,PGF,THY1,NRP1,PDGFRA
GO:0048646 anatomical structure formation 3.00e-02 3 7 234 14467 PGF,THY1,NRP1
GO:0035295 tube development 3.23e-02 3 7 240 14467 PGF,NRP1,PDGFRA		 GO:0030198 extracellular matrix organization and biogenesis 6.40e-04 3 9 64 21198 TNXB,COL3A1,PDGFRA
GO:0007160 cell-matrix adhesion 3.02e-03 3 9 107 21198 TNXB,COL3A1,THY1
GO:0007167 enzyme linked receptor protein signaling pathway 3.33e-03 4 9 375 21198 COL3A1,PDGFRA,SEMA3C,NRP1
GO:0031589 cell-substrate adhesion 3.46e-03 3 9 112 21198 TNXB,COL3A1,THY1
GO:0007275 multicellular organismal development 3.53e-03 7 9 2603 21198 COL3A1,PDGFRA,SEMA3A,SEMA3C,THY1,PGF,NRP1
GO:0050771 negative regulation of axonogenesis 3.67e-03 2 9 13 21198 THY1,NRP1
GO:0022610 biological adhesion 3.88e-03 5 9 878 21198 TNXB,COL3A1,ISLR,THY1,NRP1
GO:0007155 cell adhesion 3.88e-03 5 9 878 21198 TNXB,COL3A1,ISLR,THY1,NRP1
GO:0043062 extracellular structure organization and biogenesis 4.26e-03 3 9 120 21198 TNXB,COL3A1,PDGFRA
GO:0001525 angiogenesis 9.35e-03 3 9 156 21198 THY1,PGF,NRP1
GO:0030199 collagen fibril organization 9.85e-03 2 9 21 21198 TNXB,COL3A1
GO:0009887 organ morphogenesis 1.01e-02 4 9 497 21198 PDGFRA,THY1,PGF,NRP1
GO:0048731 system development 1.23e-02 6 9 1969 21198 COL3A1,PDGFRA,SEMA3A,THY1,PGF,NRP1
GO:0035295 tube development 1.53e-02 3 9 184 21198 PDGFRA,PGF,NRP1
GO:0032963 collagen metabolic process 1.64e-02 2 9 27 21198 TNXB,COL3A1
GO:0048514 blood vessel morphogenesis 1.71e-02 3 9 191 21198 THY1,PGF,NRP1
GO:0050768 negative regulation of neurogenesis 1.77e-02 2 9 28 21198 THY1,NRP1
GO:0048646 anatomical structure formation 1.99e-02 3 9 201 21198 THY1,PGF,NRP1
GO:0001568 blood vessel development 2.53e-02 3 9 218 21198 THY1,PGF,NRP1
GO:0048856 anatomical structure development 2.56e-02 6 9 2238 21198 COL3A1,PDGFRA,SEMA3A,THY1,PGF,NRP1
GO:0001944 vasculature development 2.67e-02 3 9 222 21198 THY1,PGF,NRP1
GO:0032502 developmental process 2.74e-02 7 9 3532 21198 COL3A1,PDGFRA,SEMA3A,SEMA3C,THY1,PGF,NRP1
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 3.66e-02 3 9 247 21198 PDGFRA,SEMA3C,NRP1
GO:0050770 regulation of axonogenesis 3.83e-02 2 9 41 21198 THY1,NRP1
GO:0048513 organ development 4.77e-02 5 9 1477 21198 COL3A1,PDGFRA,THY1,PGF,NRP1