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Subnetworks conserved in human and mouse

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Mouse Subnetwork Human Subnetwork
G 10560 TERF1 1421 SMARCAD1 10560--1421 11699 2610028A01RIK 10560--11699 701 SALL1 10560--701 4897 XRCC6 1962 GCN5L2 4897--1962 3033 TERT 4897--3033 5055 HDAC1 4897--5055 357 SMARCA2 357--1962 139 ATRX 357--139 357--1421 357--5055 1962--1421 1962--701 1962--5055 139--1421 2285 EZH2 139--2285 1421--2285 1421--701 1421--5055 2285--5055 11699--3033 701--5055 G 10560 TERF1 139 ATRX 10560--139 2285 EZH2 10560--2285 701 SALL1 10560--701 4897 XRCC6 1962 GCN5L2 4897--1962 3033 TERT 4897--3033 5055 HDAC1 4897--5055 357 SMARCA2 357--139 1421 SMARCAD1 357--1421 139--1421 139--2285 2285--5055 701--5055
Cytoscape file Cytoscape file

Confidence Information

Average fold change (normalized) 0.166726
Number of real subnetworks at this score 169
Number of random subnetworks at this score 5.60 +/- 3.28

Mouse genes' details

Gene Name Actual fold change Normalized fold change
TERF1 2.48 0.60
XRCC6 1.13 0.13
SMARCA2 0.47 -0.22
GCN5L2 1.28 0
ATRX 0 0
SMARCAD1 1.65 0.12
EZH2 1.21 0.04
2610028A01RIK 1.33 0.17
TERT 1.92 0.26
SALL1 1.92 0.16
HDAC1 1.35 0.18

Human genes' details

Gene Name Absolute fold change Normalized fold change
TERF1telomeric repeat binding factor (NIMA-interacting) 1 3.98 0.60
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 6 1.36 0.13
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.60 -0.22
GCN5L2K(lysine) acetyltransferase 2A 0 0
ATRXalpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) 0 0
SMARCAD1SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1.32 0.12
EZH2nhancer of zeste homolog 2 (Drosophila) 1.10 0.04
TERTtelomerase reverse transcriptase 1.80 0.26
SALL1al-like 1 (Drosophila) 1.44 0.16
HDAC1histone deacetylase 1 1.50 0.18

Go Enrichment

Mouse GO Terms Human GO Terms
GO:0006278 RNA-dependent DNA replication 1.15e-06 3 10 7 14467 TERF1,TERT,2610028A01RIK
GO:0006259 DNA metabolic process 5.77e-06 6 10 357 14467 SMARCAD1,ATRX,TERF1,TERT,2610028A01RIK,XRCC6
GO:0051276 chromosome organization and biogenesis 2.79e-04 5 10 357 14467 SMARCA2,TERF1,EZH2,HDAC1,2610028A01RIK
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 7.93e-04 9 10 3002 14467 SALL1,SMARCAD1,ATRX,TERF1,EZH2,TERT,HDAC1,2610028A01RIK,XRCC6
GO:0007004 telomere maintenance via telomerase 8.89e-04 2 10 6 14467 TERF1,2610028A01RIK
GO:0050794 regulation of cellular process 3.25e-03 9 10 3527 14467 SALL1,SMARCA2,SMARCAD1,ATRX,TERF1,EZH2,HDAC1,2610028A01RIK,XRCC6
GO:0043170 macromolecule metabolic process 5.82e-03 10 10 5286 14467 SALL1,SMARCA2,SMARCAD1,ATRX,TERF1,EZH2,TERT,HDAC1,2610028A01RIK,XRCC6
GO:0050789 regulation of biological process 6.81e-03 9 10 3839 14467 SALL1,SMARCA2,SMARCAD1,ATRX,TERF1,EZH2,HDAC1,2610028A01RIK,XRCC6
GO:0032200 telomere organization and biogenesis 1.12e-02 2 10 20 14467 TERF1,2610028A01RIK
GO:0000723 telomere maintenance 1.12e-02 2 10 20 14467 TERF1,2610028A01RIK
GO:0006260 DNA replication 1.34e-02 3 10 138 14467 TERF1,TERT,2610028A01RIK
GO:0043283 biopolymer metabolic process 1.44e-02 9 10 4186 14467 SALL1,SMARCAD1,ATRX,TERF1,EZH2,TERT,HDAC1,2610028A01RIK,XRCC6
GO:0065007 biological regulation 1.67e-02 9 10 4258 14467 SALL1,SMARCA2,SMARCAD1,ATRX,TERF1,EZH2,HDAC1,2610028A01RIK,XRCC6
GO:0006996 organelle organization and biogenesis 4.30e-02 5 10 1013 14467 SMARCA2,TERF1,EZH2,HDAC1,2610028A01RIK		 GO:0016568 chromatin modification 8.17e-06 5 10 236 21198 HDAC1,SMARCAD1,GCN5L2,EZH2,TERF1
GO:0051276 chromosome organization and biogenesis 8.86e-06 6 10 524 21198 HDAC1,SMARCAD1,GCN5L2,TERT,EZH2,TERF1
GO:0045449 regulation of transcription 1.05e-04 9 10 3339 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.32e-04 9 10 3427 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.44e-04 10 10 5138 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,TERT,XRCC6,EZH2,TERF1,ATRX
GO:0006350 transcription 1.48e-04 9 10 3472 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0006325 establishment and/or maintenance of chromatin architecture 1.54e-04 5 10 426 21198 HDAC1,SMARCAD1,GCN5L2,EZH2,TERF1
GO:0010468 regulation of gene expression 1.59e-04 9 10 3498 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0031323 regulation of cellular metabolic process 3.37e-04 9 10 3810 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0019222 regulation of metabolic process 4.47e-04 9 10 3934 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0006259 DNA metabolic process 2.69e-03 5 10 764 21198 SMARCAD1,TERT,XRCC6,TERF1,ATRX
GO:0043283 biopolymer metabolic process 3.13e-03 10 10 6990 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,TERT,XRCC6,EZH2,TERF1,ATRX
GO:0010467 gene expression 3.60e-03 9 10 4989 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0006996 organelle organization and biogenesis 5.28e-03 6 10 1560 21198 HDAC1,SMARCAD1,GCN5L2,TERT,EZH2,TERF1
GO:0050794 regulation of cellular process 9.24e-03 9 10 5559 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0050789 regulation of biological process 1.54e-02 9 10 5896 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX
GO:0006310 DNA recombination 1.90e-02 3 10 198 21198 SMARCAD1,XRCC6,ATRX
GO:0006355 regulation of transcription, DNA-dependent 2.30e-02 7 10 3091 21198 HDAC1,SALL1,SMARCA2,GCN5L2,XRCC6,EZH2,ATRX
GO:0051252 regulation of RNA metabolic process 2.41e-02 7 10 3112 21198 HDAC1,SALL1,SMARCA2,GCN5L2,XRCC6,EZH2,ATRX
GO:0032200 telomere organization and biogenesis 2.45e-02 2 10 35 21198 TERT,TERF1
GO:0000723 telomere maintenance 2.45e-02 2 10 35 21198 TERT,TERF1
GO:0006351 transcription, DNA-dependent 2.68e-02 7 10 3164 21198 HDAC1,SALL1,SMARCA2,GCN5L2,XRCC6,EZH2,ATRX
GO:0032774 RNA biosynthetic process 2.72e-02 7 10 3170 21198 HDAC1,SALL1,SMARCA2,GCN5L2,XRCC6,EZH2,ATRX
GO:0051260 protein homooligomerization 3.53e-02 2 10 42 21198 SMARCAD1,TERF1
GO:0065007 biological regulation 4.05e-02 9 10 6594 21198 HDAC1,SALL1,SMARCA2,SMARCAD1,GCN5L2,XRCC6,EZH2,TERF1,ATRX