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Subnetworks conserved in human and mouse

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Mouse Subnetwork Human Subnetwork
G 2272 POSTN 527 COL1A2 2272--527 292 LAMA4 2272--292 9764 DCN 38 FBN1 9764--38 8936 PDGFC 9764--8936 9764--527 1146 PDGFRA 9764--1146 38--8936 38--527 38--292 38--1146 8936--527 2131 CDH11 8936--2131 8936--1146 527--2131 527--292 527--1146 2131--1146 10428 TNFAIP6 G 2272 POSTN 38 FBN1 2272--38 527 COL1A2 2272--527 2131 CDH11 2272--2131 292 LAMA4 2272--292 1146 PDGFRA 2272--1146 10428 TNFAIP6 2272--10428 9764 DCN 9764--38 9764--527 9764--292 38--527 38--2131 38--292 38--1146 38--10428 8936 PDGFC 8936--1146 527--2131 527--292 527--1146 527--10428 2131--292 2131--1146 2131--10428 292--1146 292--10428 1146--10428
Cytoscape file Cytoscape file

Confidence Information

Average fold change (normalized) 0.237775
Number of real subnetworks at this score 28
Number of random subnetworks at this score 0.60 +/- 0.72

Mouse genes' details

Gene Name Actual fold change Normalized fold change
POSTN 0.39 -0.40
DCN 0.66 -0.70
FBN1 0.57 -0.44
PDGFC 1.45 -0.24
COL1A2 0.68 -0.20
CDH11 0.41 -0.23
LAMA4 0.27 -0.41
PDGFRA 0.56 -0.32
TNFAIP6 1.06 0

Human genes' details

Gene Name Absolute fold change Normalized fold change
POSTNperiostin, osteoblast specific factor 0.40 -0.40
DCNdecorin 0.20 -0.70
FBN1fibrillin 1 0.37 -0.44
PDGFCplatelet derived growth factor C 0.58 -0.24
COL1A2collagen, type I, alpha 2 0.63 -0.20
CDH11cadherin 11, type 2, OB-cadherin (osteoblast) 0.58 -0.23
LAMA4laminin, alpha 4 0.38 -0.41
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide 0.48 -0.32
TNFAIP6tumor necrosis factor, alpha-induced protein 6 0 0

Go Enrichment

Mouse GO Terms Human GO Terms
GO:0048008 platelet-derived growth factor receptor signaling pathway 5.60e-03 2 8 19 14467 PDGFC,PDGFRA
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.44e-02 3 8 189 14467 COL1A2,PDGFC,PDGFRA
GO:0022610 biological adhesion 2.32e-02 4 8 608 14467 LAMA4,POSTN,TNFAIP6,CDH11
GO:0007155 cell adhesion 2.32e-02 4 8 608 14467 LAMA4,POSTN,TNFAIP6,CDH11
GO:0007167 enzyme linked receptor protein signaling pathway 4.89e-02 3 8 286 14467 COL1A2,PDGFC,PDGFRA		 GO:0048513 organ development 6.36e-07 8 9 1477 21198 FBN1,DCN,PDGFRA,LAMA4,COL1A2,CDH11,POSTN,PDGFC
GO:0048731 system development 6.24e-06 8 9 1969 21198 FBN1,DCN,PDGFRA,LAMA4,COL1A2,CDH11,POSTN,PDGFC
GO:0048856 anatomical structure development 1.72e-05 8 9 2238 21198 FBN1,DCN,PDGFRA,LAMA4,COL1A2,CDH11,POSTN,PDGFC
GO:0007275 multicellular organismal development 5.67e-05 8 9 2603 21198 FBN1,DCN,PDGFRA,LAMA4,COL1A2,CDH11,POSTN,PDGFC
GO:0001501 skeletal development 3.39e-04 4 9 255 21198 FBN1,COL1A2,CDH11,POSTN
GO:0032502 developmental process 6.25e-04 8 9 3532 21198 FBN1,DCN,PDGFRA,LAMA4,COL1A2,CDH11,POSTN,PDGFC
GO:0048008 platelet-derived growth factor receptor signaling pathway 7.95e-04 2 9 9 21198 PDGFRA,PDGFC
GO:0032501 multicellular organismal process 1.44e-03 8 9 3930 21198 FBN1,DCN,PDGFRA,LAMA4,COL1A2,CDH11,POSTN,PDGFC
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.72e-02 3 9 247 21198 PDGFRA,COL1A2,PDGFC
GO:0022610 biological adhesion 4.30e-02 4 9 878 21198 LAMA4,CDH11,POSTN,TNFAIP6
GO:0007155 cell adhesion 4.30e-02 4 9 878 21198 LAMA4,CDH11,POSTN,TNFAIP6
GO:0018108 peptidyl-tyrosine phosphorylation 4.54e-02 2 9 65 21198 PDGFRA,PDGFC
GO:0018212 peptidyl-tyrosine modification 4.82e-02 2 9 67 21198 PDGFRA,PDGFC